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Updated: Oct 20, 2026
Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
Published on: August 9, 2016
Laparoscopic vs. open resection of gastrointestinal stromal tumors (GISTs) from gastric origin: different approaches
Fausto Rosa1,2, Riccardo Ricci3,4, Federica Galiandro5
1Department of Digestive Surgery, IRCCS A. Gemelli University Polyclinic Foundation, Rome, Italy - fausto.rosa@policlinicogemelli.it.
Background:
Although minimally-invasive techniques are currently recognized as effective and validated treatment for small gastric gastrointestinal stromal tumors (GISTs), the role of laparoscopy is not yet established. The aim of this study was to evaluate the outcomes of laparoscopic treatment of gastric GISTs compared to the results obtained in a group of patients treated with conventional surgery.
Methods:
A retrospective analysis was performed, using a prospectively maintained comprehensive database of 100 patients treated for gastric GIST in the period from 2000 to 2015. Thirty-six patients were treated laparoscopically, and 64 patients underwent conventional surgery. The analyzed medical data included clinical and pathological features of removed tumors, perioperative parameters as well as short and long-term results of surgical treatment.
Results:
Histopathological examination confirmed radical resections for all patients. No deaths were reported in the 90-day postoperative period. Patients in laparoscopic group had significantly shorter length of hospital stay (5.5 vs. 7 days, P<0.0001), fewer extended and combined surgical procedures (11.2% vs. 34.4% and 2.8% vs. 39%; P=0.02 and P<0.001, respectively), and a smaller tumor size compared to laparotomic group (3 vs. 6 cm, P<0.0001). The median postoperative follow-up for the entire study population was 42 months. During this period, 11 patients died and 4 of them developed a tumor recurrence. None of them was in the laparoscopic group.
Conclusions:
Laparoscopy in the treatment of gastric GISTs has unquestionable advantages, but its choice is strictly related to tumor features.
Insights
Laparoscopic surgery for gastric gastrointestinal stromal tumors (GISTs) offers significant advantages, including shorter hospital stays and no recurrence in a study comparing it to conventional surgery. The choice of laparoscopy depends on tumor characteristics.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Minimally invasive techniques are effective for small gastric GISTs.
- The role of laparoscopy for gastric GISTs requires further establishment.
- This study compares laparoscopic to conventional surgery for gastric GISTs.
Purpose of the Study:
- To evaluate the outcomes of laparoscopic treatment for gastric GISTs.
- To compare laparoscopic surgery results with conventional surgery for gastric GISTs.
Main Methods:
- Retrospective analysis of 100 gastric GIST patients (2000-2015).
- 36 patients underwent laparoscopic surgery; 64 had conventional surgery.
- Analysis included tumor features, perioperative parameters, and short/long-term results.
Main Results:
- All resections were radical; no 90-day postoperative deaths.
- Laparoscopic group had shorter hospital stays (5.5 vs. 7 days).
- Laparoscopic surgery involved fewer complex procedures and smaller tumors, with no recurrences during follow-up.
Conclusions:
- Laparoscopic treatment of gastric GISTs offers clear benefits.
- The selection of laparoscopy for gastric GISTs is contingent on tumor features.
