ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts
Insoo Hyun1, Ellen Wright Clayton2, Yali Cong3
1Department of Bioethics, Case Western Reserve University School of Medicine, Cleveland, OH, USA; Center for Bioethics, Harvard Medical School, Boston, MA, USA.
Stem Cell Reports
|May 28, 2021
Abstract:
The newly revised 2021 ISSCR Guidelines for Stem Cell Research and Clinical Translation includes scientific and ethical guidance for the transfer of human pluripotent stem cells and their direct derivatives into animal models. In this white paper, the ISSCR subcommittee that drafted these guidelines for research involving the use of nonhuman embryos and postnatal animals explains and summarizes their recommendations.


