[Interobserver comparison of quantitative analysis of local wall function of the left ventricle in stress...

During diagnostic heart catheterization biplane cineventriculograms of 46 patients at rest and directly after bicycle ergometry (72.8 +/- 27.8 W) were performed. The aim of the study was to determine the value of local wall motion analysis under physical exercise. Therefore two observers independently analyzed global and local left ventricular parameters. 38 patients had coronary artery disease, 23 with a history of myocardial infarction. Enddiastolic (EDV) and endsystolic volume (ESV) were evaluated and ejection fraction (EF) was calculated. Local wall motion was analyzed using a radial model with 60 radii in the 30 degrees RAO- and 60 degrees LAO-Projektion. A systolic segmental shortening was determined for the anterobasal (AB), anterolateral (AL), apical (AP), diaphragmatic (DP), posterobasal (PB) (30 degrees-RAO), septal (SE) and posterolateral (PL) area (60 degrees-LAO). Global functional parameters (EDV, ESV, EF) revealed good correlations between both observers with correlation coefficients (r) varying from 0.83 to 0.92. Local wall motion had sufficient correlations (r) at rest and during exercise (data in brackets) in the RAO-projektion: AB: 0.88 (0.73), AL: 0.69 (0.72), AP: 0.82 (0.78), DP: 0.77 (0.75), PB: 0.78 (0.78) and in the septal segment (LAO-projection): 0.69 (0.71). Less sufficient correlations were found in the posterolateral segment (LAO, especially at rest: 0.50 (0.69). Thus, global ventricular parameters can be determined at rest and during exercise independently of the observer. Local wall motion, too, can be quantified with sufficient accuracy with exception of the posterolateral area in the LAO-projektion.