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Acetic Acid Supplementation: Effect on Resting and Exercise Energy Expenditure and Substrate Utilization.

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Short-term apple cider vinegar (ACV) supplementation did not significantly alter resting or exercise energy expenditure or substrate utilization in healthy individuals. This study found no impact of 4-day ACV intake on metabolic rate during rest or cycling exercise.

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Area of Science:

  • Nutritional Biochemistry
  • Human Physiology
  • Metabolic Studies

Background:

  • Emerging research suggests chronic acetic acid (apple cider vinegar; ACV) supplementation may reduce body weight and fat.
  • The impact of short-term ACV supplementation on energy metabolism remains less understood.

Purpose of the Study:

  • To investigate the effects of 4-day apple cider vinegar supplementation on resting and exercise energy expenditure.
  • To assess the influence of ACV on substrate utilization during rest and submaximal cycling exercise.

Main Methods:

  • A randomized, double-blind, crossover study involving 16 healthy subjects.
  • Subjects received either 30-ml/d of ACV or a placebo for 4 days.
  • Indirect calorimetry was used to measure resting energy expenditure (REE), exercise energy expenditure (EEE), and substrate utilization during rest and cycling at 40W and 80W.

Main Results:

  • No significant differences were observed in REE or resting substrate utilization between ACV and placebo groups (p ≥ .05).
  • Exercise energy expenditure (EEE-40 and EEE-80) and substrate utilization (carbohydrate and fat) during cycling were not significantly different between groups (p ≥ .05).

Conclusions:

  • Semi-acute (4-day) supplementation with apple cider vinegar does not appear to affect resting or exercise energy expenditure.
  • ACV supplementation for 4 days did not alter substrate utilization during rest or exercise in healthy individuals.