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The Psoriasis Decision Tree.

George Monks1,2, Ryan Rivera-Oyola1,2, Mark Lebwohl1,2

  • 1Dr. Monks is with the Department of Dermatology, University of Oklahoma College of Medicine in Oklahoma City, Oklahoma.

The Journal of Clinical and Aesthetic Dermatology
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Summary
This summary is machine-generated.

Psoriasis patients often have other health issues, like psoriatic arthritis or heart disease. This review helps doctors choose the best psoriasis treatments based on these specific patient comorbidities.

Keywords:
Psoriasisacitretinbiologicsbrodalumabcomorbiditiescyclosporinedepressionguselkumabinflammatory bowel diseaseixekizumabkidney diseaseliver diseasemethotrexatemultiple sclerosispregnancypsoriatic arthritisrisankizumabsecukinumabtildrakizumabustekinumab

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Area of Science:

  • Dermatology
  • Immunology
  • Internal Medicine

Background:

  • Psoriasis is a chronic inflammatory skin condition.
  • It is linked to numerous systemic diseases (comorbidities), including psoriatic arthritis, psychiatric disorders, malignancy, cardiometabolic, and inflammatory bowel diseases.
  • Managing psoriasis requires considering these comorbidities for effective treatment selection.

Purpose of the Study:

  • To review evidence-based guidelines for psoriasis treatment in patients with specific comorbidities.
  • To provide a visual aid for selecting optimal psoriasis therapies tailored to individual patient needs and co-existing conditions.

Main Methods:

  • Systematic review of evidence-based guidelines for psoriasis treatment.
  • Consolidation of treatment recommendations based on common psoriasis comorbidities.
  • Development of a visual tool to aid clinical decision-making.

Main Results:

  • Psoriasis comorbidities significantly influence treatment selection.
  • Specific therapeutic options are better suited for patients with certain co-existing conditions.
  • A visual aid can simplify and enhance the confidence of physicians in choosing individualized psoriasis treatments.

Conclusions:

  • Optimal psoriasis management necessitates a comprehensive approach that accounts for associated systemic diseases.
  • Evidence-based guidelines and decision-support tools are crucial for tailoring therapy to patients with psoriasis and comorbidities.
  • Individualized treatment strategies improve patient outcomes by addressing both psoriasis and its related health conditions.