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An Orthotopic Model of Murine Bladder Cancer
Published on: February 6, 2011
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Isolated bladder metastasis from lung adenocarcinoma: a case report
Selim Zaghbib1, Marouene Chakroun1, Ahmed Saadi1
1Department of Urology, Charles Nicolle Hospital, Tunis, Tunisia.
Journal of Surgical Case Reports
|May 31, 2021
Summary
Metastasis to the bladder from distant cancers, like pulmonary adenocarcinoma, is rare. This case highlights a rare instance of bladder cancer secondary to lung adenocarcinoma, emphasizing the need for thorough diagnosis.
Area of Science:
- Urology
- Oncology
- Pulmonology
Background:
- Bladder neoplasms are rarely from extravesical origins (2-12%).
- Distant metastasis to the bladder is exceptional, particularly from pulmonary adenocarcinoma.
Observation:
- A 55-year-old male with diagnosed pulmonary adenocarcinoma presented with macroscopic hematuria.
- Imaging revealed a lung mass and bladder wall thickening.
- Cystoscopy showed inflammatory lesions on the bladder mucosa.
Findings:
- Biopsy confirmed tumoral proliferation in the bladder lamina propria.
- Immunohistochemical examination matched the bladder tumor profile to the primary lung tumor (CK7+/TTF1+/CK20-/PSA-).
Implications:
- This case underscores the rare possibility of pulmonary adenocarcinoma metastasizing to the bladder.
- Accurate immunohistochemical profiling is crucial for diagnosing secondary bladder tumors.
- Early identification and appropriate treatment strategies are vital for improving patient outcomes in rare metastatic cases.
