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Predictive Factors in Sacral Neuromodulation: A Systematic Review.

Ranjana Jairam1, Jamie Drossaerts1, Tom Marcelissen1

  • 1Department of Urology, Maastricht University Medical Centre (MUMC+), Mastricht, The Netherlands.

Urologia Internationalis
|May 31, 2021
PubMed
Summary
This summary is machine-generated.

Sacral neuromodulation (SNM) shows promise for overactive bladder, with female gender, younger age, and tined leads potentially predicting success. However, no definitive predictors were established, necessitating further research.

Keywords:
Lower urinary tract symptomsNonobstructive urinary retentionOveractive bladderPredictive factorsSacral neuromodulation

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Area of Science:

  • Urology
  • Neuromodulation
  • Evidence-based medicine

Background:

  • Sacral neuromodulation (SNM) is a treatment for overactive bladder syndrome and nonobstructive urinary retention.
  • Identifying factors predicting SNM success is crucial for optimizing patient outcomes.
  • This review synthesizes evidence on predictive factors for SNM.

Approach:

  • Systematic review conducted following PRISMA guidelines.
  • Registered in PROSPERO (CRD42015016256).
  • Included 78 studies (11 abstracts) with evidence levels primarily rated as 3b.

Key Points:

  • Female patients, younger age, and tined lead procedures may predict successful SNM outcomes.
  • Prior back surgery, stress urinary incontinence surgery, affective symptoms, and complaint duration did not influence outcomes.
  • Reduced detrusor contractility is associated with lower SNM success rates.

Conclusions:

  • No general consensus on predictive factors for SNM was reached due to study limitations.
  • Most included studies were small, retrospective, and used heterogeneous populations.
  • Prospective research in larger, specific patient groups is required to establish reliable SNM outcome predictors.