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Published on: August 8, 2022
Prevalence of hypertrophic cardiomyopathy in a large sample of the Spanish working population
J Rodríguez-Capitán1, A Fernández-Meseguer2, P Márquez-Camas1
1UGC Área del Corazón, Servicio de Cirugía Cardiovascular y Cardiología, Hospital Universitario Virgen de la Victoria, Málaga, Spain; Instituto Biosanitario de Málaga (IBIMA), CIBERCV Enfermedades Cardiovasculares, Instituto de Salud Carlos III, Madrid, Spain.
Insights
This study found hypertrophic cardiomyopathy (HCM) affects 0.24% of Spain's working population. Among those without hypertension, the prevalence of HCM was 0.19%.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Hypertrophic cardiomyopathy (HCM) is a significant cardiac condition with unknown prevalence in Spain's general population.
- Previous epidemiological studies on HCM in Spain are lacking, necessitating research in diverse population subsets.
Purpose of the Study:
- To determine the prevalence of hypertrophic cardiomyopathy (HCM) within a large, working-age population sample in Spain.
- To specifically assess HCM prevalence in individuals without a history of hypertension.
Main Methods:
- A cohort of 13,179 Spanish workers underwent electrocardiogram (ECG) screening.
- Individuals with abnormal ECGs or relevant medical history were referred for echocardiography.
- Hypertrophic cardiomyopathy was defined as left ventricular parietal thickness ≥13mm.
Main Results:
- A total of 16 cases of hypertrophic cardiomyopathy were identified, yielding an overall prevalence of 0.24%.
- In the subgroup of workers without hypertension, 10 cases were detected, resulting in a prevalence of 0.19%.
- Echocardiographic evaluation was completed by 496 of the 1008 workers referred.
Conclusions:
- The estimated prevalence of hypertrophic cardiomyopathy in the studied Spanish working population is 0.24%.
- The prevalence of HCM in the normotensive subgroup was found to be 0.19%.
Background And Objectives:
To date, in Spain, there are no studies that have evaluated the prevalence of hypertrophic cardiomyopathy in the general population. The aim of this study was to assess the prevalence of hypertrophic cardiomyopathy in a large sample of the working population of Spain.
Materials And Methods:
The study included 13,179 workers (73% men; mean age: 40 years) from 5 regions of Spain who, between May 2008 and November 2010, had a medical examination with an electrocardiogram. The workers with suggestive abnormalities in the electrocardiogram or a predisposing medical history (exertional syncope or sudden death of a family member younger than 50 years) were referred for an echocardiographic evaluation. We defined hypertrophic cardiomyopathy as a parietal thickness ≥13mm in any segment of the left ventricle. We estimated the prevalence of hypertrophic cardiomyopathy in the entire sample and in the workers without hypertension.
Results:
A total of 1008 workers were selected for the echocardiogram, although only 496 (49.2% of those selected) of these attended the appointment. After the echocardiogram, we detected 16 cases of hypertrophic cardiomyopathy, estimating a prevalence of 0.24% for the entire sample. In the subgroup of workers with no hypertension, we observed 10 cases of hypertrophic cardiomyopathy, which corresponds to an estimated prevalence of 0.19%.
Conclusions:
In our sample of the working population in Spain, the estimated prevalence of hypertrophic cardiomyopathy was 0.24%. In the subgroup of patients with no hypertension, the estimated prevalence was 0.19%.
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