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Related Experiment Videos

Second-screening mammography: one versus two views per breast.

D M Ikeda1, E A Sickles

  • 1Department of Radiology, University of California School of Medicine, San Francisco 94143.

Radiology
|September 1, 1988
PubMed
Summary

For women with dense breasts, one-view mammography leads to more false positives than two-view. For fatty breasts, one-view may be cost-effective for screening, but cancer detection rates are unknown.

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Area of Science:

  • Radiology
  • Medical Imaging
  • Breast Cancer Screening

Background:

  • Mammography is a key tool for breast cancer detection.
  • Follow-up screening mammography aims to detect interval cancers and changes.
  • The optimal number of views for second-screening mammography is debated.

Purpose of the Study:

  • To compare the diagnostic yield and cost-effectiveness of one-view versus two-view mammography for second screening.
  • To evaluate the impact of breast density on the interpretation of one-view versus two-view mammography.

Main Methods:

  • Retrospective review of 1,000 asymptomatic women's mammograms (oblique and craniocaudal views).
  • Analysis of interpretations using one-view (oblique only) versus two-view (oblique and craniocaudal) protocols.
  • Comparison of abnormal interpretation rates and associated costs based on breast density.

Main Results:

  • In women with dense breasts, one-view readings yielded abnormal interpretations 4x more frequently (5.3%) than two-view (1.3%).
  • These false positives in dense breasts would negate cost savings from one-view screening.
  • In women with fatty breasts, one-view readings were less frequent (1.3%), suggesting potential cost-effectiveness for this group.

Conclusions:

  • One-view mammography is less effective for dense breasts, leading to unnecessary follow-up costs.
  • One-view mammography may be considered for follow-up screening in women with fatty breasts based on cost.
  • Further research is needed to determine the sensitivity of one-view versus two-view screening for breast cancer detection.

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