Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A β-hairpin mimic built on a fluorinated isoxazoline-β<sup>2,2</sup>-amino acid as a modulator of Tau protein aggregation.

Organic & biomolecular chemistry·2026
Same author

Sustainable electrochemical synthesis of a new isoxazoline scaffold as turn inducer to build parallel β-hairpins.

Organic & biomolecular chemistry·2026
Same author

Late-stage peptide modification with salicylaldehyde tag enhances affinity for nuclear factor-kappa B essential modulator.

RSC chemical biology·2025
Same author

Ultrathin water layers on mannosylated gold nanoparticles.

Beilstein journal of nanotechnology·2025
Same author

Synthetic chaperone based on Hsp90-Tau interaction inhibits Tau aggregation and rescues physiological Tau-Microtubule interaction.

Nature communications·2025
Same author

Innovative On-Resin and in Solution Peptidomimetics Synthesis via Metal-Free Photocatalytic Approach.

Chemistry (Weinheim an der Bergstrasse, Germany)·2024

Related Experiment Video

Updated: Nov 3, 2025

Vapor Phase Deposition of Electroactive Poly(3,4-ethylenedioxythiophene) onto Electrospun Commodity Polymer Nanofibers
08:28

Vapor Phase Deposition of Electroactive Poly(3,4-ethylenedioxythiophene) onto Electrospun Commodity Polymer Nanofibers

Published on: March 7, 2025

1.4K

Peptide-Based Electrospun Fibers: Current Status and Emerging Developments.

Raffaella Bucci1, Evangelos Georgilis2, Alexander M Bittner2,3

  • 1Department of Pharmaceutical Sciences, University of Milan, Via Venezian 21, 20133 Milan, Italy.

Nanomaterials (Basel, Switzerland)
|June 2, 2021
PubMed
Summary

Electrospinning can create uniform fibers from peptides, not just high molecular weight polymers. This review explores the growing use of self-assembling peptides in electrospun nanofibers for diverse applications.

Keywords:
electrospinningpeptide-based electrospun nanofiberspeptidespeptidomimeticsself-assembly

More Related Videos

Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections
12:21

Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections

Published on: October 31, 2017

7.6K
Postproduction Processing of Electrospun Fibres for Tissue Engineering
15:52

Postproduction Processing of Electrospun Fibres for Tissue Engineering

Published on: August 9, 2012

18.4K

Related Experiment Videos

Last Updated: Nov 3, 2025

Vapor Phase Deposition of Electroactive Poly(3,4-ethylenedioxythiophene) onto Electrospun Commodity Polymer Nanofibers
08:28

Vapor Phase Deposition of Electroactive Poly(3,4-ethylenedioxythiophene) onto Electrospun Commodity Polymer Nanofibers

Published on: March 7, 2025

1.4K
Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections
12:21

Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections

Published on: October 31, 2017

7.6K
Postproduction Processing of Electrospun Fibres for Tissue Engineering
15:52

Postproduction Processing of Electrospun Fibres for Tissue Engineering

Published on: August 9, 2012

18.4K

Area of Science:

  • Materials Science
  • Biotechnology
  • Nanotechnology

Background:

  • Electrospinning is a versatile technique for creating polymer fibers.
  • Uniform electrospun fibers depend on intermolecular interactions, not solely high molecular weight.
  • Small molecules, particularly self-assembling peptides, can also be electrospun into fibers.

Purpose of the Study:

  • To review the state-of-the-art in peptide electrospinning since the early 2000s.
  • To discuss the advantages and disadvantages of using peptides for electrospun nanofibers.
  • To present characterization techniques specific to peptide fibers.

Main Methods:

  • Literature review of electrospinning techniques applied to peptides.
  • Analysis of studies focusing on peptide self-assembly for fiber formation.
  • Compilation of characterization methods for peptide-based nanofibers.

Main Results:

  • Peptides, including those with natural and non-natural amino acids, are increasingly used in electrospinning.
  • The field is transitioning from basic research to practical applications.
  • Key factors for successful peptide electrospinning and fiber properties are identified.

Conclusions:

  • Peptide-based electrospun nanofibers offer a promising new class of materials.
  • Understanding peptide self-assembly and intermolecular forces is crucial for successful electrospinning.
  • Further research and characterization are needed to fully realize the potential of peptide nanofibers.