Cardiovascular Stents: A Review of Past, Current, and Emerging Devices

Alexandru Scafa Udriște1,2, Adelina-Gabriela Niculescu3, Alexandru Mihai Grumezescu4,5

  • 1Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Insights

Coronary artery disease treatments have advanced from bare-metal stents to drug-eluting and bioresorbable stents. This review explores stent evolution to optimize vascular scaffolds for better patient outcomes.

Area of Science:

  • Cardiovascular medicine
  • Biomaterials science
  • Medical device engineering

Background:

  • Coronary artery disease (CAD) is a major global health issue, causing significant morbidity and mortality.
  • Plaque buildup narrows arteries, impeding blood flow and oxygen supply to the heart.
  • Vascular stents are the standard treatment, providing vessel support to maintain patency.

Purpose of the Study:

  • To review the historical progression of vascular stent technology.
  • To analyze the advancements from bare-metal stents to modern drug-eluting and bioresorbable stents.
  • To identify areas for optimization in creating ideal vascular scaffolds.

Main Methods:

  • Literature review of stent development and clinical outcomes.
  • Analysis of material science and engineering innovations in stent design.
  • Evaluation of the impact of different stent generations on patient health.

Main Results:

  • Stent technology has evolved significantly, improving patient outcomes and reducing adverse effects.
  • Drug-eluting stents (DES) reduce restenosis rates compared to bare-metal stents (BMS).
  • Bioresorbable vascular scaffolds (BVS) offer a potential for vessel recovery but face challenges.

Conclusions:

  • Continuous innovation in stent design is crucial for managing coronary artery disease.
  • Future research should focus on optimizing stent materials and drug delivery for long-term efficacy.
  • The development of an ideal vascular scaffold remains an ongoing pursuit in interventional cardiology.