Related Experiment Video
Updated: Nov 3, 2025

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
Published on: October 26, 2016
Cardiovascular Stents: A Review of Past, Current, and Emerging Devices
Alexandru Scafa Udriște1,2, Adelina-Gabriela Niculescu3, Alexandru Mihai Grumezescu4,5
1Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Insights
Coronary artery disease treatments have advanced from bare-metal stents to drug-eluting and bioresorbable stents. This review explores stent evolution to optimize vascular scaffolds for better patient outcomes.
Area of Science:
- Cardiovascular medicine
- Biomaterials science
- Medical device engineering
Background:
- Coronary artery disease (CAD) is a major global health issue, causing significant morbidity and mortality.
- Plaque buildup narrows arteries, impeding blood flow and oxygen supply to the heart.
- Vascular stents are the standard treatment, providing vessel support to maintain patency.
Purpose of the Study:
- To review the historical progression of vascular stent technology.
- To analyze the advancements from bare-metal stents to modern drug-eluting and bioresorbable stents.
- To identify areas for optimization in creating ideal vascular scaffolds.
Main Methods:
- Literature review of stent development and clinical outcomes.
- Analysis of material science and engineering innovations in stent design.
- Evaluation of the impact of different stent generations on patient health.
Main Results:
- Stent technology has evolved significantly, improving patient outcomes and reducing adverse effects.
- Drug-eluting stents (DES) reduce restenosis rates compared to bare-metal stents (BMS).
- Bioresorbable vascular scaffolds (BVS) offer a potential for vessel recovery but face challenges.
Conclusions:
- Continuous innovation in stent design is crucial for managing coronary artery disease.
- Future research should focus on optimizing stent materials and drug delivery for long-term efficacy.
- The development of an ideal vascular scaffold remains an ongoing pursuit in interventional cardiology.
Abstract:
One of the leading causes of morbidity and mortality worldwide is coronary artery disease, a condition characterized by the narrowing of the artery due to plaque deposits. The standard of care for treating this disease is the introduction of a stent at the lesion site. This life-saving tubular device ensures vessel support, keeping the blood-flow path open so that the cardiac muscle receives its vital nutrients and oxygen supply. Several generations of stents have been iteratively developed towards improving patient outcomes and diminishing adverse side effects following the implanting procedure. Moving from bare-metal stents to drug-eluting stents, and recently reaching bioresorbable stents, this research field is under continuous development. To keep up with how stent technology has advanced in the past few decades, this paper reviews the evolution of these devices, focusing on how they can be further optimized towards creating an ideal vascular scaffold.
Related Concept Videos
Cardiac Catheterization I: Pre-Procedure Overview
Coronary Artery Disease V: Interprofessional Care

