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Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis
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Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis

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Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists

Robert Adam1,2, Gabriela Neculae1, Claudiu Stan2,3

  • 1Expert Center for Rare Genetic Cardiovascular Diseases, Department of Cardiology, "Prof. Dr. C.C. Iliescu" Emergency Institute for Cardiovascular Diseases, 022328 Bucharest, Romania.

Diagnostics (Basel, Switzerland)
|June 2, 2021
PubMed

Insights

Cardiac amyloidosis (CA) is increasingly recognized, yet Romanian cardiologists show varied knowledge and limited experience. Educational initiatives are crucial to improve early diagnosis and treatment of this condition.

Area of Science:

  • Cardiology
  • Amyloidosis Research
  • Medical Education

Background:

  • Cardiac amyloidosis (CA) is a restrictive cardiomyopathy caused by amyloid deposition in the heart muscle.
  • Recent studies indicate CA is more prevalent than previously thought.
  • Advances in diagnosis and treatment necessitate prompt identification of CA.

Purpose of the Study:

  • To assess the current knowledge and experience of Romanian cardiologists regarding cardiac amyloidosis.
  • To identify gaps in understanding CA, including specific types like transthyretin amyloidosis (ATTRwt and ATTRv).
  • To highlight educational needs for improving CA diagnosis and management.

Main Methods:

  • An online survey was distributed to cardiologists in Romania.
  • 195 cardiologists completed the questionnaire on their knowledge and experience with CA.
  • The survey assessed awareness of CA prevalence, diagnosis, and treatment options.

Main Results:

  • Significant variation in knowledge about CA was observed among participants.
  • Romanian cardiologists reported limited experience with CA and noted delays in diagnosis.
  • Gaps were identified in understanding ATTRwt and ATTRv prevalence, diagnosis, and treatment.

Conclusions:

  • Cardiologist awareness is a key challenge in diagnosing CA.
  • Romanian cardiologists possess partial awareness but require further education on CA.
  • Targeted educational programs can enhance patient screening and improve outcomes for CA.

Keywords:
ATTRamyloidosisawarenesscardiologistsurvey

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