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Related Experiment Videos

Acute atrophic glossitis after open-heart surgery.

L Bengtsson1, U Ransjö

  • 1Department of Thoracic Surgery, Karolinska Hospital, Stockholm, Sweden.

Scandinavian Journal of Thoracic and Cardiovascular Surgery
|January 1, 1988
PubMed
Summary

Postoperative acute atrophic glossitis (AAG) is linked to Candida albicans infections in cardiac surgery patients. Prompt nystatin treatment effectively resolved AAG in all affected individuals.

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Area of Science:

  • Medical Microbiology
  • Immunology
  • Cardiovascular Surgery

Background:

  • Candida infections pose significant risks, particularly in patients undergoing transplant surgery and immunosuppression.
  • Acute atrophic glossitis (AAG) is a common postoperative complication observed in cardiac surgery patients.

Purpose of the Study:

  • To investigate the source of postoperative AAG in cardiac surgery patients.
  • To determine the association between Candida albicans and AAG development post-cardiac surgery.

Main Methods:

  • Clinical and microbiologic investigations were conducted on 33 patients before and after cardiac surgery (coronary artery bypass or valve replacement).
  • Cultures were analyzed for Candida albicans presence.
  • Postoperative AAG incidence and clinical presentation were monitored.

Main Results:

  • 12 out of 33 patients had preoperative Candida albicans-positive cultures, and all developed AAG postoperatively.
  • An additional 6 patients with negative preoperative cultures also developed postoperative AAG.
  • All 18 patients with AAG showed positive response to topical nystatin treatment.
  • No cases of disseminated candidiasis were observed.

Conclusions:

  • Candida albicans colonization is a likely source of postoperative AAG in cardiac surgery patients.
  • Topical nystatin is an effective treatment for AAG in this patient population.
  • Postoperative AAG in cardiac surgery patients, while common, does not appear to lead to disseminated candidiasis.

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