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Updated: Nov 3, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Psoriasis: From Pathogenesis to Pharmacological and Nano-Technological-Based Therapeutics
Robert Gironés Petit1, Amanda Cano1,2,3, Alba Ortiz1,2
1Department of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy, University of Barcelona, 08028 Barcelona, Spain.
Recent breakthroughs in understanding inflammatory skin diseases like psoriasis have led to new treatments. Nanotechnology and microneedles show promise for targeted drug delivery in psoriasis management.
Area of Science:
- Dermatology and immunology, focusing on inflammatory skin conditions.
Background:
- Psoriasis and dermatitis are complex inflammatory skin diseases influenced by age, gender, and genetics.
- Recent research has advanced the understanding of their pathogenesis, enabling new therapeutic strategies.
Purpose of the Study:
- To review the molecular mechanisms of psoriasis pathogenesis.
- To discuss current and emerging therapies for psoriasis and other chronic inflammatory skin diseases.
Main Methods:
- Literature review of recent advancements in psoriasis research.
- Analysis of novel therapeutic approaches, including nanotechnological drug delivery and microneedles.
Main Results:
- Understanding of multifactorial disease influences has driven therapeutic innovation.
- Nanotechnology offers enhanced drug concentration at disease sites.
- Microneedles present a promising drug delivery system for inflammatory skin conditions.
Conclusions:
- Innovative therapies are emerging for inflammatory skin diseases.
- Nanotechnology and microneedles represent significant advancements in targeted drug delivery for psoriasis and related conditions.
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