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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

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A Rapid and Chemical-free Hemoglobin Assay with Photothermal Angular Light Scattering
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Phototheranostics Using Erythrocyte-Based Particles.

Taylor Hanley1, Raviraj Vankayala1,2, Chi-Hua Lee3

  • 1Department of Bioengineering, University of California, Riverside, CA 92521, USA.

Biomolecules
|June 2, 2021
PubMed
Summary
This summary is machine-generated.

Red blood cell (RBC) delivery systems offer immune evasion for light-activated imaging and therapies. This review covers fabrication methods and current applications with future clinical potential.

Keywords:
cancerdelivery systemsimagingphotodynamic therapyphotothermal therapyred blood cells

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Photomedicine

Background:

  • Red blood cells (RBCs) are being engineered into novel delivery systems.
  • These RBC-based constructs leverage natural immune evasion properties.
  • Incorporating optical components enables light-mediated activation.

Purpose of the Study:

  • To review fabrication methods for RBC-based delivery systems.
  • To present current light-based applications of these constructs.
  • To discuss future directions and clinical translation potential.

Main Methods:

  • Review of existing literature on RBC engineering techniques.
  • Analysis of studies utilizing light-activated RBC constructs.
  • Synthesis of information on fabrication and application.

Main Results:

  • Common fabrication methods for RBC delivery systems are detailed.
  • Current light-mediated imaging and therapeutic applications are presented.
  • Potential for clinical translation is highlighted.

Conclusions:

  • RBC-based delivery systems are a promising area of research.
  • Light-activation offers unique advantages for targeted therapies and imaging.
  • Further development could lead to significant clinical advancements.