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Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
What Is New with Total Pancreatectomy and Autologous Islet Cell Transplantation? Review of Current Progress in the
Xavier L Baldwin1, Brittney M Williams1, Beth Schrope2
1Department of Surgery, University of North Carolina in Chapel Hill, Chapel Hill, NC 27599, USA.
Patients with chronic pancreatitis have benefited from total pancreatectomy and autologous islet cell transplantation (TPAIT) since the 1970s. Over the past few decades, improvements have been made in surgical technique and perioperative management that have led to improved success of islet cell function, insulin independence and patient survival. This article focuses on recent updates and advances for the TPAIT procedure that continue to expand and innovate the impact on patients with debilitating disease.
Patients with chronic pancreatitis have benefited from total pancreatectomy and autologous islet cell transplantation (TPAIT) since the 1970s. Over the past few decades, improvements have been made in surgical technique and perioperative management that have led to improved success of islet cell function, insulin independence and patient survival. This article focuses on recent updates and advances for the TPAIT procedure that continue to expand and innovate the impact on patients with debilitating disease.

