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Recombination within the class III region by a double cross over event
M Rose1, G R Menzel, G Geserick
1Institute of Forensic Medicine, School of Medicine (Charité), Humboldt University, Berlin, GDR.
Tissue Antigens
|April 1, 1988
Abstract:
Analysis of class I, class II, and class III gene products of the human MHC in a Caucasoid family with four children gave evidence for a double crossing over event in monozygotic twins between the C2, Bf/C4A, C4B gene loci. In view of the small genetic distance between C2 and C4, a point mutation within the Bf locus must be considered alternatively.