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Genomics

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

Proteomics

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...

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Related Experiment Video

Updated: Nov 3, 2025

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Published on: May 30, 2019

Malaria in the 'Omics Era'.

Mirko Pegoraro¹, Gareth D Weedall¹

¹School of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK.

|June 2, 2021

Summary

This summary is machine-generated.

Genomic sequencing of the malaria parasite Plasmodium falciparum revolutionized parasitic disease research. Continued Plasmodium genomics studies offer deep insights into parasite biology, evolution, and population genetics.

Keywords:

Plasmodium genomics malaria methylation methylomics

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Last Updated: Nov 3, 2025

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Area of Science:

Parasitology
Genomics
Evolutionary Biology

Background:

Genomics has transformed the study of parasitic diseases.
The malaria parasite, Plasmodium falciparum, was the first eukaryotic parasite to undergo genome sequencing.
Plasmodium genomics has advanced parasite genome biology research through extensive sequencing.

Purpose of the Study:

To review insights gained from Plasmodium genome sequencing.
To explore the impact of genomics on understanding parasite biology, evolution, and population genetics.
To identify future directions for genome-scale studies in Plasmodium.

Main Methods:

Genome sequencing of multiple Plasmodium species.
Massive-scale genome re-sequencing of key Plasmodium species.
Review of existing genomic data and research findings.

Main Results:

Genome sequencing has provided significant insights into Plasmodium biology.
Genomic data has illuminated the evolution and population genetics of Plasmodium parasites.
The breadth and depth of Plasmodium genome sequencing have advanced the field.

Conclusions:

Plasmodium genomics continues to be a leading area in parasitic disease research.
Genome sequencing offers a powerful tool for understanding parasite biology and evolution.
Future genome-scale studies hold promise for further discoveries in Plasmodium.