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Updated: Nov 3, 2025

Quantification of Bacterial Histidine Kinase Autophosphorylation Using a Nitrocellulose Binding Assay
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Nitrate- and Nitrite-Sensing Histidine Kinases: Function, Structure, and Natural Diversity.

Ivan Gushchin1, Vladimir A Aleksenko1, Philipp Orekhov1,2

  • 1Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, 141700 Dolgoprudny, Russia.

International Journal of Molecular Sciences
|June 2, 2021
PubMed
Summary

Bacteria use nitrate- and nitrite-sensing histidine kinases (NSHKs) to detect electron acceptors. This review details NSHK diversity, structure, and function across various bacterial groups, including those in anaerobic ammonia oxidation communities.

Keywords:
allosterycell signalinghistidine kinasesnitrate regulationnitrate respirationsignal transductiontwo-component systems

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