Implementation and Rationale for a Unified Clinical and Imaging Protocol for Evaluation and Treatment of Moyamoya

Anthony S Larson1, Vance T Lehman1, Luis E Savastano2

  • 1Department of Radiology, Mayo Clinic, Rochester, MN, United States.

Insights

Moyamoya disease (MMD) evaluation is complex due to its rarity. This study details a comprehensive, multidisciplinary protocol to improve patient assessment and care for Moyamoya disease.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Radiology

Background:

  • Moyamoya disease (MMD) is a rare, complex cerebrovascular disorder.
  • Establishing effective evaluation protocols for MMD is challenging, even at specialized centers.
  • A structured, multidisciplinary approach is crucial for optimal MMD patient management.

Purpose of the Study:

  • To describe the implementation and rationale of a comprehensive multidisciplinary evaluation strategy for adult Moyamoya disease patients.
  • To outline a detailed protocol for the thorough clinical, imaging, and referral process in MMD.

Main Methods:

  • Implementation of a multidisciplinary collaboration and evaluation strategy.
  • Initial thorough clinical and laboratory assessment by a vascular neurologist.
  • Comprehensive imaging evaluation including angiographic, parenchymal, and cerebrovascular functionality assessment.
  • Referrals to specialized consulting services, including vascular neurosurgery.

Main Results:

  • The described protocol facilitates a systematic and thorough evaluation of adult Moyamoya disease patients.
  • Integration of clinical, imaging, and surgical expertise ensures comprehensive patient assessment.
  • The strategy aims to optimize diagnostic accuracy and treatment planning for MMD.

Conclusions:

  • A comprehensive, multidisciplinary evaluation protocol is essential for managing Moyamoya disease.
  • This structured approach enhances the evaluation and treatment of adult MMD patients.
  • The described strategy provides a model for specialized centers dealing with rare cerebrovascular conditions.

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