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Early outcomes of patient-prosthesis mismatch following aortic valve replacement

Serik Aitaliyev1, Egle Rumbinaitė2, Karolina Mėlinytė-Ankudavičė2

  • 1Department of Cardiac, Thoracic and Vascular Surgery, Hospital of Lithuanian University of Health Sciences Kauno Klinikos, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Perfusion
|June 3, 2021
PubMed
Abstract

Insights

Patient-prosthesis mismatch (PPM) after aortic valve replacement (AVR) was common but did not impact early outcomes. Further research is needed to understand the long-term effects of residual PPM.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Biomedical Engineering

Background:

  • Patient-prosthesis mismatch (PPM) is linked to adverse events after aortic valve replacement (AVR).
  • Understanding PPM's impact on early postoperative results is crucial for clinical practice.

Purpose of the Study:

  • To evaluate the effect of PPM on early postoperative results in patients undergoing AVR.
  • To determine the incidence of moderate and severe PPM in a real-world clinical setting.

Main Methods:

  • A retrospective analysis of 150 patients undergoing AVR between March 2019 and January 2020.
  • PPM was categorized based on indexed effective orifice area: severe (<0.65 cm²/m²), moderate (0.65-0.85 cm²/m²), and none (>0.85 cm²/m²).
  • Outcomes assessed included operative mortality and complication rates.

Main Results:

  • Moderate PPM was observed in 10.6% of patients; severe PPM was not found.
  • PPM was not significantly associated with early mortality, or intra- and postoperative complications.

Conclusions:

  • Moderate PPM is a frequent finding after AVR, but severe PPM is rare in this cohort.
  • PPM did not influence early postoperative outcomes following AVR in this study.
  • Long-term follow-up in a larger patient cohort is necessary to fully ascertain the impact of residual PPM.
Keywords:
AVRPPMaortic valveheart valve prosthesisresultsvalve hemodynamic

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