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COMMD5 Inhibits Malignant Behavior of Renal Cancer Cells.

Jin Ikeda1, Hiroyuki Matsuda2, Maiko Ogasawara1

  • 1Division of General Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.

Anticancer Research
|June 4, 2021
PubMed
Summary

Copper metabolism MURR1 domain-containing 5 (COMMD5) suppresses renal cell carcinoma (RCC) by reducing cancer stemness and malignant phenotypes. Low COMMD5 levels correlate with poor patient outcomes, suggesting COMMD5 as a potential therapeutic target.

Keywords:
COMMD5cancer stem cellmetastasis and recurrencerenal cell carcinomarenal tubules

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