The impact of COVID-19 on pregnancy and therapeutic drug development

Allyah Abbas-Hanif1,2, Homira Rezai1, Syed Faraz Ahmed1

  • 1Division of Drug Development, MirZyme Therapeutics, Birmingham, UK.

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Teratogenicity01:07

Teratogenicity

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A drug interaction occurs when the concurrent use of another drug, food, or an external substance alters the pharmacological activity of a drug. This interaction can modify the action of the original drug, affecting its effectiveness and safety.Drug–food interactions are significant as they impact drug absorption, metabolism, and excretion. For example, grapefruit juice is a well-known disruptor of drug metabolism. It inhibits the cytochrome P450 3A4 enzyme, crucial for the metabolism of...
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