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Related Concept Videos

Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

301
Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
301

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Standardized endpoint definitions for trials of transcatheter left atrial appendage closure: a consensus from the Left Atrial Appendage Academic Research Consortium†.

European heart journal·2026
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External Suture-Retention Device Versus Manual Compression for Venous Access-Site Closure Post-Ablation: The LockeT II Study.

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Pre-clinical impact of higher irrigation flow rates during pulsed field ablation with a variable loop circular catheter.

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Related Experiment Video

Updated: Nov 3, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

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Current practice and future prospects in left atrial appendage occlusion.

Bharat Narasimhan1,2, Surya Kiran Aedma3, Kirtipal Bhatia1,2

  • 1Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Pacing and Clinical Electrophysiology : PACE
|June 4, 2021
PubMed
Summary

Left atrial appendage occlusion offers a safe alternative to anticoagulation for preventing strokes in atrial fibrillation (AF) patients. This minimally invasive procedure addresses bleeding risks and compliance issues associated with traditional therapies.

Keywords:
atrial fibrillationendocardial approachesepicardial approachesleft atrial appendage occlusion

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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
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Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
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Last Updated: Nov 3, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Area of Science:

  • Cardiology
  • Medical Devices
  • Interventional Cardiology

Background:

  • Atrial fibrillation (AF) poses significant thromboembolic risks, often managed with anticoagulation.
  • Anticoagulant therapy presents challenges including bleeding risks and medication compliance.
  • The left atrial appendage (LAA) is a primary source of emboli in AF.

Purpose of the Study:

  • To review the evolution and current status of left atrial appendage occlusion (LAAO).
  • To discuss devices and procedural advancements in LAAO.
  • To evaluate LAAO as an alternative to systemic anticoagulation in non-valvular AF.

Main Methods:

  • Review of existing literature on LAAO.
  • Analysis of data from landmark trials and ongoing research.
  • Evaluation of commercially available LAA occlusion devices.

Main Results:

  • LAAO is emerging as a safe, effective, and feasible alternative to systemic anticoagulation for stroke prevention in AF.
  • Procedural safety and efficacy have improved with increasing experience and device development.
  • LAAO offers non-thrombotic advantages, expanding its potential indications.

Conclusions:

  • Left atrial appendage occlusion is a viable strategy for mitigating thromboembolic events in AF patients.
  • Ongoing research and technological advancements continue to refine LAAO.
  • LAAO represents a significant development in the management of AF patients at risk of stroke.