Multi-subsite receptors for multivalent ligands. Application to drugs, hormones, and neurotransmitters

RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder.

Molecular psychiatry·2014

Upregulation of α-synuclein during localized radiation therapy signals the association of cancer-related fatigue with the activation of inflammatory and neuroprotective pathways.

Brain, behavior, and immunity·2012

Cooperative and redundant signaling of leukotriene B4 and leukotriene D4 in human monocytes.

Allergy·2011

Glycaemic variability is associated with coronary artery calcium in men with Type 1 diabetes: the Coronary Artery Calcification in Type 1 Diabetes study.

Diabetic medicine : a journal of the British Diabetic Association·2010

Transcriptome analysis and molecular signature of human retinal pigment epithelium.

Human molecular genetics·2010

Distinct gene expression profiles in norepinephrine- and epinephrine-producing hereditary and sporadic pheochromocytomas: activation of hypoxia-driven angiogenic pathways in von Hippel-Lindau syndrome.

Endocrine-related cancer·2004

ZD-4009, a novel B-cell lymphoma 9 inhibitor, is associated with ameliorated pulmonary fibrosis and reduced hypoxia-inducible factor 1α-mediated glycolysis and transforming growth factor-β/SMAD signaling.

Molecular pharmacology·2026

Piezo1 agonists are potent off-target inhibitors of the Kv1.3 channel via gating modification.

Molecular pharmacology·2026

Panoramic characterization of proposed ligands for GPR3: oleoylethanolamide as a pharmacological chaperone.

Molecular pharmacology·2026

Roles of the phosphorylation sites of distinct α1A-adrenergic receptor domains.

Molecular pharmacology·2026

A-kinase anchoring protein complexes and cAMP signaling within the dorsal root ganglia in chronic pain.

Molecular pharmacology·2026

An integrated structural and functional profiling approach uncovers the mechanisms of pregnane X receptor binding and activation by pharmaceutical and environmental compounds.

Molecular pharmacology·2026

UK Medical Cannabis Registry: An Updated Analysis of Inflammatory Arthritis.

Clinical medicine insights. Arthritis and musculoskeletal disorders·2026

A novel multi-aptamer electrospun nanofibrous membrane for simultaneous selective extraction of monoamine neurotransmitters and determination in biological samples by LC-MS.

Analytical and bioanalytical chemistry·2026

Pharmacological modulation of GPR84 revealed by dual states structures and immune functional assays.

Experimental & molecular medicine·2026

Structural basis of active state coupling of metabotropic glutamate receptor 8 to beta-arrestins.

Nature communications·2026

Unraveling Cadaverine Toxicity Effect to Guide the Engineering of Robust Strain.

Metabolic engineering·2026

Pharmacological actions of novel beta-lactam and non-beta lactam compounds on major astrocytic glutamate transporters in the brain and liver of male C57BL/6 mice exposed chronically to hydrocodone.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026

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Multi-subsite receptors for multivalent ligands. Application to drugs, hormones, and neurotransmitters

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RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder.

Upregulation of α-synuclein during localized radiation therapy signals the association of cancer-related fatigue with the activation of inflammatory and neuroprotective pathways.

Cooperative and redundant signaling of leukotriene B4 and leukotriene D4 in human monocytes.

Glycaemic variability is associated with coronary artery calcium in men with Type 1 diabetes: the Coronary Artery Calcification in Type 1 Diabetes study.

Transcriptome analysis and molecular signature of human retinal pigment epithelium.

Distinct gene expression profiles in norepinephrine- and epinephrine-producing hereditary and sporadic pheochromocytomas: activation of hypoxia-driven angiogenic pathways in von Hippel-Lindau syndrome.

ZD-4009, a novel B-cell lymphoma 9 inhibitor, is associated with ameliorated pulmonary fibrosis and reduced hypoxia-inducible factor 1α-mediated glycolysis and transforming growth factor-β/SMAD signaling.

Piezo1 agonists are potent off-target inhibitors of the Kv1.3 channel via gating modification.

Panoramic characterization of proposed ligands for GPR3: oleoylethanolamide as a pharmacological chaperone.

Roles of the phosphorylation sites of distinct α1A-adrenergic receptor domains.

A-kinase anchoring protein complexes and cAMP signaling within the dorsal root ganglia in chronic pain.

An integrated structural and functional profiling approach uncovers the mechanisms of pregnane X receptor binding and activation by pharmaceutical and environmental compounds.

UK Medical Cannabis Registry: An Updated Analysis of Inflammatory Arthritis.

A novel multi-aptamer electrospun nanofibrous membrane for simultaneous selective extraction of monoamine neurotransmitters and determination in biological samples by LC-MS.

Pharmacological modulation of GPR84 revealed by dual states structures and immune functional assays.

Structural basis of active state coupling of metabotropic glutamate receptor 8 to beta-arrestins.

Unraveling Cadaverine Toxicity Effect to Guide the Engineering of Robust Strain.

Pharmacological actions of novel beta-lactam and non-beta lactam compounds on major astrocytic glutamate transporters in the brain and liver of male C57BL/6 mice exposed chronically to hydrocodone.

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Multi-subsite receptors for multivalent ligands. Application to drugs, hormones, and neurotransmitters

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