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Apoptotic signals at the endoplasmic reticulum-mitochondria interface.

Flavia Giamogante1, Elena Poggio1, Lucia Barazzuol1

  • 1Department of Biomedical Sciences, University of Padova, Padova, Italy.

Advances in Protein Chemistry and Structural Biology
|June 6, 2021
PubMed
Summary

Mitochondria-associated ER membranes (MAMs) are crucial for maintaining cellular homeostasis. Disruptions in MAMs can trigger apoptosis, a programmed cell death process, highlighting their role in cell survival regulation.

Keywords:
ApoptosisBioenergeticsCalcium signalingER-mitochondria contact sitesMAMsOrganelle tethering

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