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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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The diabetic muscle.

Sanjay Kalra1, Saptarshi Bhattacharya2, Rajneesh Mittal3

  • 1Department of Endocrinology, Bharti Hospital, Karnal, India.

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Skeletal muscle plays a key role in viscerometabolic health and diabetes. Understanding muscle

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insulin resistance, insulin sensitizers, liraglutide, semaglutide, striated muscle, metformin, pioglitazone, physical activity.

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Area of Science:

  • Physiology
  • Endocrinology
  • Metabolic Health

Background:

  • Skeletal muscle is integral to overall health.
  • It significantly influences and is influenced by viscerometabolic status.
  • Dysfunction is linked to metabolic diseases.

Purpose of the Study:

  • To elucidate the multifaceted role of skeletal muscle.
  • To detail its involvement in diabetes pathophysiology.
  • To outline clinical presentation and management strategies.

Main Methods:

  • Structured literature review and discussion.
  • Analysis of existing research on muscle and diabetes.
  • Synthesis of current understanding.

Main Results:

  • Skeletal muscle impacts glucose homeostasis.
  • Muscle wasting and dysfunction are common in diabetes.
  • Therapeutic strategies targeting muscle are crucial.

Conclusions:

  • Skeletal muscle is a critical factor in diabetes.
  • Interventions promoting muscle health can improve outcomes.
  • Further research into muscle-specific therapies is warranted.