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Updated: Nov 2, 2025

Identification of Post-translational Modifications of Plant Protein Complexes
Published on: February 22, 2014
Tandem Protein Kinases Emerge as New Regulators of Plant Immunity
Valentyna Klymiuk1, Gitta Coaker2, Tzion Fahima3,4
1Crop Development Centre and Department of Plant Sciences, University of Saskatchewan, Saskatoon, SK S7N 5A8, Canada.
Abstract:
Plant-pathogen interactions result in disease development in a susceptible host. Plants actively resist pathogens via a complex immune system comprising both surface-localized receptors that sense the extracellular space as well as intracellular receptors recognizing pathogen effectors. To date, the majority of cloned resistance genes encode intracellular nucleotide-binding leucine-rich repeat receptor proteins. Recent discoveries have revealed tandem kinase proteins (TKPs) as another important family of intracellular proteins involved in plant immune responses. Five TKP genes-barley Rpg1 and wheat WTK1 (Yr15), WTK2 (Sr60), WTK3 (Pm24), and WTK4-protect against devastating fungal diseases. Moreover, a large diversity and numerous putative TKPs exist across the plant kingdom. This review explores our current knowledge of TKPs and serves as a basis for future studies that aim to develop and exploit a deeper understanding of innate plant immunity receptor proteins.[Formula: see text] Copyright © 2021 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license.
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