Pulmonary leiomyomatosis showing endobronchial extension and giant cyst formation

A 49-year-old woman who had previously undergone hysterectomy was found to have multiple pulmonary masses and cysts and experienced respiratory failure. Bronchoscopic study revealed an endobronchial mass obstructing the left main bronchus and protruding into the trachea. She was treated with an endoscopic laser to eliminate the airway obstruction. After recovery from the respiratory failure, two-stage thoracotomies were performed at six-month intervals. The endobronchial mass originated from a tumor in the left basal segment. The histologic findings on the cysts and nodules of both lungs were compatible with fibroleiomyoma. The final diagnosis was pulmonary leiomyomatosis with myoma uteri.