Six-year outcomes of carotid artery stenting performed with multidisciplinary management in a single center

Erkan Köklü1, Şakir Arslan1, Elif Sarıönder Gencer2

  • 1Department of Cardiology, University of Health Sciences, Antalya Training and Research Hospital; Antalya-Turkey.

Insights

Carotid artery stenting (CAS) is a safe and effective treatment for both symptomatic and asymptomatic carotid artery stenosis, showing high success rates and acceptable complications in real-world data. This multidisciplinary approach ensures reliable outcomes for diverse patient groups.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Neurology

Background:

  • Carotid artery stenosis poses a significant risk for stroke.
  • Carotid artery stenting (CAS) is an alternative to endarterectomy.
  • Real-world data on CAS outcomes, including asymptomatic cranial embolism and restenosis, are crucial.

Purpose of the Study:

  • To evaluate the 30-day clinical outcomes of CAS.
  • To assess periprocedural asymptomatic cranial embolism.
  • To determine long-term restenosis rates after CAS in a real-world patient cohort.

Main Methods:

  • A consecutive series of 610 patients undergoing CAS between 2010 and 2019 were analyzed.
  • Patients were followed for a mean of 6 years, with stratification into symptomatic (45%) and asymptomatic (55%) groups.
  • Embolism protection devices were utilized in varying percentages (distal 52%, proximal 43%).

Main Results:

  • The CAS procedure achieved a 96% success rate with low procedure-related mortality (0.6%).
  • Clinical complication rates within 30 days were 1.6% in asymptomatic and 3.1% in symptomatic patients.
  • Cranial MRI revealed asymptomatic microembolism in 11.6% (ipsilateral) and 3.9% experienced asymptomatic restenosis.

Conclusions:

  • CAS is a reliable treatment for carotid artery stenosis, offering acceptable success and complication rates.
  • Multidisciplinary evaluation is key to successful CAS application, even in high-risk patients.
  • The procedure demonstrates efficacy in both symptomatic and asymptomatic individuals, aligning with established guidelines.
Abstract

Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
68
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
87
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
84
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
74
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
69