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Updated: Nov 2, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Six-year outcomes of carotid artery stenting performed with multidisciplinary management in a single center
Erkan Köklü1, Şakir Arslan1, Elif Sarıönder Gencer2
1Department of Cardiology, University of Health Sciences, Antalya Training and Research Hospital; Antalya-Turkey.
Insights
Carotid artery stenting (CAS) is a safe and effective treatment for both symptomatic and asymptomatic carotid artery stenosis, showing high success rates and acceptable complications in real-world data. This multidisciplinary approach ensures reliable outcomes for diverse patient groups.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Neurology
Background:
- Carotid artery stenosis poses a significant risk for stroke.
- Carotid artery stenting (CAS) is an alternative to endarterectomy.
- Real-world data on CAS outcomes, including asymptomatic cranial embolism and restenosis, are crucial.
Purpose of the Study:
- To evaluate the 30-day clinical outcomes of CAS.
- To assess periprocedural asymptomatic cranial embolism.
- To determine long-term restenosis rates after CAS in a real-world patient cohort.
Main Methods:
- A consecutive series of 610 patients undergoing CAS between 2010 and 2019 were analyzed.
- Patients were followed for a mean of 6 years, with stratification into symptomatic (45%) and asymptomatic (55%) groups.
- Embolism protection devices were utilized in varying percentages (distal 52%, proximal 43%).
Main Results:
- The CAS procedure achieved a 96% success rate with low procedure-related mortality (0.6%).
- Clinical complication rates within 30 days were 1.6% in asymptomatic and 3.1% in symptomatic patients.
- Cranial MRI revealed asymptomatic microembolism in 11.6% (ipsilateral) and 3.9% experienced asymptomatic restenosis.
Conclusions:
- CAS is a reliable treatment for carotid artery stenosis, offering acceptable success and complication rates.
- Multidisciplinary evaluation is key to successful CAS application, even in high-risk patients.
- The procedure demonstrates efficacy in both symptomatic and asymptomatic individuals, aligning with established guidelines.
Objective:
This study aimed to evaluate the first 30-day results of clinical, periprocedural asymptomatic cranial embolism, and long-term restenosis of the multidisciplinary conducted and evaluated carotid artery stenting (CAS) procedure in our patient group with real-life data.
Methods:
A total of 610 patients who were subjected to consecutive CAS procedures in our center between December 2010 and February 2019 were clinically and radiologically followed up for a mean duration of 6 years. Of the 610 patients, 274 (45%) were symptomatic for carotid artery stenosis, whereas 336 (55%) were identified as asymptomatic. As embolism protection methods, distal protection, proximal protection, and double (distal + proximal) protection was used in 52%, 43%, and 0.3% of patients, respectively.
Results:
The success rate of the CAS procedure was 96%. Procedure-related death was reported in 4 (0.6%) patients who successfully underwent the CAS procedure. Moreover, acute carotid artery stent thrombosis, hyperperfusion syndrome, periprocedural major stroke, and periprocedural minor stroke was observed in 4 (0.6%), 2 (0.3%), 2 (0.3%), and 12 (1.9%) patients, respectively. The total clinical complication rates during the first 30 periprocedural days were 1.6% (10 patients) and 3.1% (19 patients) in the asymptomatic and symptomatic groups, respectively. On cranial magnetic resonance imaging performed, asymptomatic ipsilateral cranial microembolism, asymptomatic contralateral cranial microembolism, and bilateral asymptomatic cranial microembolism was detected in 61 (11.6%), 20 (3.8%), 23 (4.4%) patients, respectively. Asymptomatic restenosis was observed in 24 (3.9%) patients.
Conclusion:
The CAS procedure is a reliable treatment option applicable with acceptable complication and success rates as outlined in the guidelines, when performed following a multidisciplinary evaluation, in the treatment of symptomatic and asymptomatic carotid artery stenosis, including high-risk patient groups.
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