Related Experiment Video

Updated: Nov 2, 2025

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
07:56

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model

Published on: January 10, 2025

850

Retraction

    Journal of Cellular Biochemistry
    |June 8, 2021
    PubMed

    Insights

    This study on bladder cancer development has been retracted due to significant flaws. The findings regarding long noncoding RNA SNHG16 are considered invalid by the journal editors.

    Area of Science:

    • Oncology
    • Molecular Biology
    • Genetics

    Context:

    • The article investigated the role of long noncoding RNA SNHG16 in bladder cancer progression.
    • It proposed a regulatory pathway involving miR-98, STAT3, and the Wnt/β-catenin signaling cascade.

    Purpose:

    • To elucidate the molecular mechanisms driving bladder cancer development.
    • To identify potential therapeutic targets based on the SNHG16 pathway.

    Summary:

    • The study has been retracted due to identified flaws and inconsistencies.
    • The editors found the presented results and experimental methods to be unreliable.
    • Consequently, the conclusions regarding SNHG16's role in bladder cancer are deemed invalid.

    Impact:

    • This retraction invalidates previous findings on the SNHG16/miR-98/STAT3/Wnt/β-catenin axis in bladder cancer.
    • It highlights the importance of rigorous validation in scientific research.
    • Researchers should exercise caution when referencing the retracted study's conclusions.

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