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Clostridium botulinum toxins: nature and preparation for clinical use
J Melling1, P Hambleton, C C Shone
1Vaccine Research and Production Laboratory, Centre for Applied Microbiology and Research, Salisbury, Wiltshire.
Eye (London, England)
|January 1, 1988
Abstract:
C. botulinum neurotoxins are acutely toxic materials and act by inhibiting release of the neurotransmitter acetylcholine. The specific nature of this inhibition is discussed and the preparation and purification of Type A toxin specifically for clinical use is described.