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Related Concept Videos

Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
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Related Experiment Video

Updated: Nov 2, 2025

Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation
10:32

Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation

Published on: July 20, 2022

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Pancreas transplantation.

Fabio Vistoli1, Emanuele F Kauffmann, Ugo Boggi

  • 1Division of General and Transplant Surgery, University of Pisa, Pisa, Italy.

Current Opinion in Organ Transplantation
|June 8, 2021
PubMed
Summary
This summary is machine-generated.

Recent pancreas transplantation (PT) practice has been shaped by the COVID-19 pandemic and a world consensus conference. Future PT activity and outcomes are expected to improve following these key events.

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Area of Science:

  • Nephrology
  • Transplantation
  • Immunology

Background:

  • The practice of pancreas transplantation (PT) has recently navigated significant global events.
  • The COVID-19 pandemic and the inaugural world consensus conference on PT have profoundly influenced its trajectory.

Purpose of the Study:

  • To delineate recent shifts and outline future strategies in pancreas transplantation.
  • To review innovative studies published post-consensus conference.

Main Methods:

  • Analysis of the impact of the COVID-19 pandemic on PT activity and outcomes.
  • Review of findings and recommendations from the first world consensus conference on PT.
  • Synthesis of recent evidence on PT efficacy, donor selection, and immunosuppression protocols.

Main Results:

  • Pancreas transplantation activity declined during the COVID-19 pandemic, with increased mortality in infected recipients.
  • The world consensus conference generated 49 jury deliberations and 110 practice recommendations.
  • Pancreas transplantation alone is safe and effective; simultaneous pancreas and kidney transplantation shows excellent results, even with older recipients and type 2 diabetes.
  • Utilizing hepatitis C virus (HCV)-positive donors for HCV-negative recipients yields good outcomes.
  • Sirolimus and costimulation blockade did not enhance simultaneous pancreas and kidney transplantation results.

Conclusions:

  • The COVID-19 pandemic temporarily impacted PT but should not deter future activity.
  • The consensus conference proceedings are anticipated to positively influence the volume and outcomes of pancreas transplantation.
  • Continued research and adherence to consensus guidelines will shape the future of pancreas transplantation.