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Inhibition of Chlamydia trachomatis growth by recombinant tumor necrosis factor
Y Shemer-Avni1, D Wallach, I Sarov
1Virology Unit, Faculty of Health Sciences, Ben-Gurion University, Beer Sheva, Israel.
Infection and Immunity
|September 1, 1988
Abstract:
Purified human recombinant tumor necrosis factor (rTNF) alpha inhibited the growth of Chlamydia trachomatis (L2/434/Bu) in HEp-2 cell cultures. The inhibition of C. trachomatis yield could be achieved even when the rTNF alpha (200 ng/ml) was added up to 12 h after infection. The effect of rTNF alpha on chlamydial infection was synergistic with that of gamma interferon.