Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Additives and Fillers in Concrete01:29

Additives and Fillers in Concrete

167
Additives and fillers are integral to enhancing the properties of concrete. Pozzolans and blast-furnace slag are additives or admixtures due to their reactions with calcium hydroxide released during cement hydration. Fillers, which are finely ground and similar in fineness to Portland cement, improve concrete attributes such as workability density, and reduce capillary bleeding or cracking. Some fillers possess hydraulic properties or participate in benign reactions within the cement paste.
The...
167
Drug Regulation01:25

Drug Regulation

2.2K
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
2.2K
Plasticizers01:31

Plasticizers

159
Water-reducers, or plasticizers, are chemical admixtures used in concrete to improve strength and workability. These additives reduce the water-cement ratio without compromising workability, lower the cement content while maintaining the same workability, or increase workability to assist concrete placement in inaccessible areas.
Plasticizers function by using surface-active agents to create repulsive electrostatic forces between cement particles. This dispersion enhances the concrete's...
159
Physical Properties of Amines01:26

Physical Properties of Amines

3.6K
Amines with low molecular weight are usually gaseous at room temperature, while those with high molecular weight are liquid or solids in nature. Usually, low molecular weight amines have a rotten fish-like smell. Diamines typically have a pungent smell. For instance, cadaverine and putrescine, depicted in Figure 1, are two molecules responsible for decaying tissue.
3.6K
FDA Approved Drugs: Changes to Approved Drugs01:26

FDA Approved Drugs: Changes to Approved Drugs

38
Post-approval, manufacturers may modify an approved new or generic drug product. Such modifications can encompass alterations in the Active Pharmaceutical Ingredient (API), manufacturing process, formulation, batch size, manufacturing site, and container closure system (FDA Guidance for Industry, April 2004). Often, a drug product may undergo multiple changes.These modifications require careful evaluation to determine their potential impact on the drug product's identity, strength, quality,...
38
Teratogenicity01:07

Teratogenicity

3.3K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Food intolerance in dogs and cats.

The Journal of small animal practice·2018
See all related articles

Related Experiment Video

Updated: Nov 2, 2025

Behavioral Disturbances: An Innovative Approach to Monitor the Modulatory Effects of a Nutraceutical Diet
07:05

Behavioral Disturbances: An Innovative Approach to Monitor the Modulatory Effects of a Nutraceutical Diet

Published on: January 3, 2017

9.1K

Additives in pet food: are they safe?

J M Craig1

  • 1Re-Fur-All Referrals, Newbury, Berkshire, RG14 7QH, UK.

The Journal of Small Animal Practice
|June 10, 2021
PubMed
Summary

Processed pet food often contains additives, raising questions about their safety and the adequacy of current testing methods. Updated strategies are needed to ensure the safety of these ingredients for pets.

Area of Science:

  • Veterinary Nutrition
  • Food Science
  • Toxicology

Background:

  • Modern domestic pets, dogs and cats, are predominantly fed highly processed diets that differ significantly from their ancestral food sources.
  • Processed pet foods incorporate various additives to enhance nutritional value, ensure safety, and maintain desirable sensory characteristics like color, flavor, and texture.
  • The distinction between synthetic and 'natural' additives can be unclear due to laboratory synthesis and extensive processing of naturally derived substances.

Purpose of the Study:

  • To review the safety of diverse additives used in processed pet food.
  • To examine current practices in pet food labeling and safety assessment.
  • To address ethical considerations associated with existing toxicity testing procedures for pet food additives.

Main Methods:

More Related Videos

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs
07:33

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs

Published on: July 6, 2015

11.6K
Using TgVtg1:mcherry Zebrafish Embryos to Test the Estrogenic Effects of Endocrine Disrupting Compounds
12:02

Using TgVtg1:mcherry Zebrafish Embryos to Test the Estrogenic Effects of Endocrine Disrupting Compounds

Published on: August 8, 2020

6.6K

Related Experiment Videos

Last Updated: Nov 2, 2025

Behavioral Disturbances: An Innovative Approach to Monitor the Modulatory Effects of a Nutraceutical Diet
07:05

Behavioral Disturbances: An Innovative Approach to Monitor the Modulatory Effects of a Nutraceutical Diet

Published on: January 3, 2017

9.1K
Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs
07:33

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs

Published on: July 6, 2015

11.6K
Using TgVtg1:mcherry Zebrafish Embryos to Test the Estrogenic Effects of Endocrine Disrupting Compounds
12:02

Using TgVtg1:mcherry Zebrafish Embryos to Test the Estrogenic Effects of Endocrine Disrupting Compounds

Published on: August 8, 2020

6.6K
  • Literature review of safety assessments for common pet food additives.
  • Analysis of regulatory frameworks for pet food ingredient labeling.
  • Evaluation of ethical implications and scientific validity of toxicity testing protocols.

Main Results:

  • Concerns are raised regarding the adequacy of safety testing for numerous additives in processed pet food.
  • The scientific basis for determining the safety of certain additives is questioned.
  • Current toxicity testing procedures face ethical scrutiny and potential limitations.

Conclusions:

  • The safety of various additives in processed pet food requires further rigorous scientific evaluation.
  • Updated strategies and advanced technologies are essential for establishing reliable safety assessments in the pet food industry.
  • A clearer distinction and regulation of synthetic versus 'natural' additives may be necessary.