Related Experiment Video
Updated: Nov 2, 2025

Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 BSL-3 Conditions
Published on: September 10, 2021
Enteric viruses seize their immunomodulatory niche
Danielle E Campbell1, Megan T Baldridge1
1Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA; Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Abstract:
Enteric eukaryotic viruses are increasingly recognized as non-pathogenic, immunomodulatory participants in the healthy intestinal microbiota. In this issue of Cell Host & Microbe, Dallari et al. (2021) use a single virus infection approach to reveal both generalized viral immune responses and numerous unique, virus-specific response profiles.
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