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Related Concept Videos

Pneumothorax-II01:27

Pneumothorax-II

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Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
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Pneumothorax-I01:26

Pneumothorax-I

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A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
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Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

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Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
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Pneumonia I: Introduction01:30

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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
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Other Pulmonary Disorders01:17

Other Pulmonary Disorders

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Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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Pulmonary Cycle: Exhalation01:17

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In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
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Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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Cannabis Use Is Associated With Recurrence After Primary Spontaneous Pneumothorax.

Connor J Wakefield1, Christopher W Seder1, Andrew T Arndt1

  • 1Department of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, IL, United States.

Frontiers in Surgery
|June 11, 2021
PubMed
Summary

Cannabis use is common in primary spontaneous pneumothorax (PSP) patients and is linked to a higher recurrence rate. This finding suggests a need for further investigation into cannabis

Keywords:
chest tube thoracostomymarijuanapneumothorax recurrencespontaneous pneumothoraxvideo-assisted thoracic surgery

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Area of Science:

  • Pulmonology
  • Thoracic Surgery
  • Addiction Medicine

Background:

  • Primary spontaneous pneumothorax (PSP) is a common condition with a significant recurrence rate.
  • Understanding risk factors for PSP recurrence is crucial for patient management.

Purpose of the Study:

  • To investigate the association between cannabis use at the time of initial PSP and disease recurrence.
  • To determine if cannabis consumption influences the likelihood of PSP recurrence.

Main Methods:

  • Retrospective study of 67 patients with PSP between 2010-2018.
  • Comparison of cannabis users versus non-users using Fisher's exact test, Wilcoxon rank-sum test, and logistic regression.
  • Adjustment for tobacco use, BMI, and height in recurrence analysis.

Main Results:

  • 42% of PSP patients reported cannabis use.
  • Cannabis users had higher rates of tobacco use and lower BMI.
  • Cannabis use was significantly associated with PSP recurrence (OR 1.85, p=0.014) after adjusting for covariates.

Conclusions:

  • A high prevalence of cannabis use exists among patients presenting with PSP.
  • Cannabis usage is an independent risk factor associated with PSP recurrence.
  • Cannabis use may predict the eventual need for operative intervention in PSP patients.