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ASO Editorial: Lymph Node Dissection in the Immunotherapy Era: Friend or Foe?
Adom Bondzi-Simpson1,2, Christopher W Seder3, Elliot Wakeam4,5
1Division of General Surgery, Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, ON, Canada. adom.bondzisimpson@mail.utoronto.ca.
Immunotherapy has changed resectable non-small cell lung cancer (NSCLC) treatment. This study explores if lymph node dissection impacts immunotherapy effectiveness by affecting immune responses crucial for cancer treatment.
Area of Science:
- Thoracic oncology
- Cancer immunology
- Surgical oncology
Background:
- Immunotherapy has revolutionized resectable non-small cell lung cancer (NSCLC) management.
- The role of surgery, specifically lymph node dissection, in modulating antitumor immunity is under renewed investigation.
- Tumor-draining lymph nodes are critical for antigen presentation and T cell priming, key components of effective immune responses.
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