Related Experiment Video

Updated: Nov 2, 2025

The Mechanics of Poro-Elastic Contractile Actomyosin Networks As a Model System of the Cell Cytoskeleton
08:50

The Mechanics of Poro-Elastic Contractile Actomyosin Networks As a Model System of the Cell Cytoskeleton

Published on: March 10, 2023

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Quantitative description of a contractile macromolecular machine.

Alec Fraser1, Nikolai S Prokhorov1, Fang Jiao2,3

  • 1Department of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics (SCSB), The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.

Science Advances
|June 12, 2021
PubMed
Summary

Contractile injection systems (CISs) breach cell membranes using a contractile sheath-tube mechanism. This study quantifies the energy, heat, and force involved in pyocin contraction, revealing the nanomachine

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