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Updated: Nov 2, 2025

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
Published on: May 6, 2010
Biology, geometry and information
Jürgen Jost1,2
1Max Planck Institute for Mathematics in the Sciences, Leipzig, Germany. jjost@mis.mpg.de.
Abstract:
The main thesis developed in this article is that the key feature of biological life is the a biological process can control and regulate other processes, and it maintains that ability over time. This control can happen hierarchically and/or reciprocally, and it takes place in three-dimensional space. This implies that the information that a biological process has to utilize is only about the control, but not about the content of those processes. Those other processes can be vastly more complex that the controlling process itself, and in fact necessarily so. In particular, each biological process draws upon the complexity of its environment.
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