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Low-dose HDACi potentiates anti-tumor activity of macrophages in immunotherapy

Xiaolei Li1, Hanren Dai1, Hua Wang1

  • 1Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Oncoimmunology
|June 14, 2021
PubMed

Keywords:
HDACicancer immunotherapytumor microenvironmenttumor-associated macrophages

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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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