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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

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Cryptogenic Fibrosing Pleuritis.

Alessandra Manco¹, Veronica Alfieri¹, Letizia Gnetti²

¹Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy.

European Journal of Case Reports in Internal Medicine

|June 14, 2021

Summary

A rare case of cryptogenic fibrosing pleuritis presented as worsening bilateral pleural effusion. High-dose corticosteroids stabilized the condition, highlighting a potential treatment for this idiopathic pleural disease.

Keywords:

Cryptogenic fibrosing pleuritis pleural effusion pleural thickening

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Area of Science:

Pulmonology
Pathology

Background:

Bilateral pleural effusion can be challenging to diagnose, especially when idiopathic.
Progressive pleural thickening can significantly impair pulmonary function.

Purpose of the Study:

To report a case of cryptogenic fibrosing pleuritis.
To discuss the diagnostic challenges and treatment outcomes for this rare pleural disease.

Main Methods:

Case report of a 46-year-old male with progressive bilateral pleural effusion.
Diagnostic workup included CT scan and pleural biopsy.
Treatment involved high-dose corticosteroids.

Main Results:

Histology revealed fibrotic tissue with inflammatory cells, excluding asbestos.
The patient's condition, diagnosed as cryptogenic fibrosing pleuritis, initially worsened despite standard treatments.
High-dose corticosteroid therapy led to disease stabilization.

Conclusions:

Cryptogenic fibrosing pleuritis is a rare cause of progressive bilateral pleural effusion and thickening.
High-dose corticosteroids may be an effective treatment, leading to stable disease.
This case underscores the importance of considering idiopathic causes in refractory pleural diseases.