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Updated: Nov 2, 2025
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Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
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Radical Prostatectomy: Sequelae in the Course of Time
Claudia Kesch1, Isabel Heidegger2, Veeru Kasivisvanathan3,4
1Department of Urology, University Hospital Essen, Essen, Germany.
Frontiers in Surgery
|June 14, 2021
Summary
Radical prostatectomy (RP) for prostate cancer (PCa) can cause erectile dysfunction and urinary incontinence. Recovery varies, with most improvement within a year, but long-term effects are possible.
Area of Science:
- Urology
- Oncology
- Quality of Life Research
Background:
- Radical prostatectomy (RP) is a primary treatment for localized prostate cancer (PCa).
- RP significantly impacts patients' health-related quality of life due to potential adverse effects.
- Understanding these side effects is crucial for patient counseling and treatment decisions.
Purpose of the Study:
- To review the common and long-term adverse effects of radical prostatectomy (RP).
- To analyze the incidence and recovery trajectories of side effects following RP for prostate cancer.
- To inform patient counseling regarding the risks and benefits of RP.
Main Methods:
- A collaborative narrative review of principal studies.
- Literature search conducted on PubMed from 2010 to February 2021 using relevant terms.
- Identification and synthesis of data on adverse events and recovery patterns.
Main Results:
- Major complication rates after RP are generally low.
- Key adverse effects include erectile dysfunction (11-87%) and urinary incontinence (0-87%), with functional decline peaking post-surgery.
- Recovery is most significant within the first year, though long-term improvements can occur; some side effects persist.
Conclusions:
- Erectile dysfunction and urinary incontinence are significant potential side effects of RP.
- The recovery trajectory for these side effects varies among patients.
- Patient counseling must address the frequency and duration of side effects to manage expectations and inform treatment choices.
Keywords:
adverse (side) effectslong-term outcomeprostate cancerretropubic radical prostatectomyrobot-assisted radical prostatectomyMore Related Videos
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