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Updated: Aug 8, 2026
Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
Case report: multimodality imaging to diagnose cardiac diffuse large B-cell lymphoma
Yahya E Alansari1, Brian Yudhistiara2, René P Michel3
1Division of Cardiology, Department of Medicine, McGill University, 1009 rue de Bleury, Apt 1009, Montréal, QC H2Z 0A3, Canada.
Background:
Primary cardiac lymphoma (PCL) is rare and can present with a wide variety of clinical symptoms, frequently leading to a delay in diagnosis.
Case Summary:
We report a case of a PCL in an 81-year-old man. Cardiac magnetic resonance imaging showed multiple masses in the right atrium and a mass in the right ventricular outflow tract extending to the pulmonary artery. Biopsy revealed a diffuse large B-cell lymphoma. The patient also had metastases to the liver and lung on the positron emission tomography-computed tomography (PET-CT) scan. He was treated with R-CHOP chemotherapy, with complete remission documented PET-CT scans.
Conclusion:
Although most patients with PCL die before chemotherapy can be initiated, a timely diagnosis can result in a favourable outcome.
