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Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
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Case report: multimodality imaging to diagnose cardiac diffuse large B-cell lymphoma.
Yahya E Alansari1, Brian Yudhistiara2, René P Michel3
1Division of Cardiology, Department of Medicine, McGill University, 1009 rue de Bleury, Apt 1009, Montréal, QC H2Z 0A3, Canada.
European Heart Journal. Case Reports
|June 14, 2021
Summary
Primary cardiac lymphoma (PCL) is rare, often delaying diagnosis. This case highlights that prompt diagnosis and R-CHOP chemotherapy can lead to complete remission in PCL patients.
Area of Science:
- Cardiology
- Oncology
- Hematology
Background:
- Primary cardiac lymphoma (PCL) is an exceptionally rare malignancy.
- PCL often presents with nonspecific symptoms, complicating early diagnosis.
Observation:
- An 81-year-old male presented with PCL involving the right atrium, right ventricular outflow tract, and pulmonary artery.
- Positron emission tomography-computed tomography (PET-CT) revealed concurrent liver and lung metastases.
Findings:
- Biopsy confirmed diffuse large B-cell lymphoma as the PCL type.
- The patient achieved complete remission following R-CHOP chemotherapy.
Implications:
- Timely diagnosis is crucial for improving outcomes in PCL.
- Aggressive chemotherapy regimens like R-CHOP can be effective even in advanced PCL cases.
