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Updated: Aug 5, 2025
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Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay
Published on: April 28, 2022
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Cutaneous T-cell lymphoma developing in surgical scars post cardiac surgery: A case study.
Sarah J Touyz1, Feras M Ghazawi2, Elena Netchiporouk3
1Department of Acute Internal Medicine, Salford Royal NHS Foundation Trust, Salford, UK.
SAGE Open Medical Case Reports
|March 27, 2023
Summary
Primary cutaneous T-cell lymphoma can develop in surgical scars months after surgery. This rare non-Hodgkin lymphoma presentation was successfully treated with radiotherapy.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Cutaneous T-cell lymphomas (CTCL) are malignant skin lymphomas with unclear pathogenesis.
- Persistent antigen stimulation and inflammatory microenvironments are implicated in CTCL development.
Observation:
- A case of primary CTCL arose in two surgical scars 6 months post-operation.
- The lesions were localized to the sites of prior surgical trauma.
Findings:
- The CTCL presented as localized disease in surgical scars.
- Successful treatment was achieved with external beam radiotherapy.
Implications:
- This case suggests CTCL can arise in surgical scars relatively quickly after trauma.
- It highlights the importance of considering CTCL in skin lesions developing at injury sites.
- This contributes to understanding CTCL development following surgery or foreign body presence.
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