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Home-based virtual reality for chronic pain: protocol for an NIH-supported randomised-controlled trial.

Brandon Birckhead¹, Sam Eberlein¹, Genie Alvarez¹

¹Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.

|June 16, 2021

Summary

This study investigates virtual reality (VR) for chronic lower back pain (cLBP). Three VR interventions will be tested to find safe, non-pharmacological, home-based pain management solutions.

Keywords:

back pain clinical trials musculoskeletal disorders pain management world wide web technology

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Area of Science:

Digital therapeutics and pain management.
Investigating virtual reality (VR) as a non-pharmacological intervention for chronic pain.
Exploring novel treatments for chronic lower back pain (cLBP).

Background:

Chronic pain, particularly cLBP, presents a significant health burden.
There is a need for safe, home-based, non-pharmacological pain management strategies.
Virtual reality (VR) shows promise for acute pain, but its efficacy in chronic pain requires further study.

Purpose of the Study:

To evaluate the effectiveness of three distinct VR interventions for patients with cLBP.
To assess VR's potential as a safe and accessible home-based treatment for chronic pain.
To identify predictors of VR efficacy in managing cLBP.

Main Methods:

A randomized trial involving 360 patients with cLBP.
Comparison of skills-based VR, distraction-based VR, and sham VR interventions over 12 weeks.
Outcomes measured via patient-reported data (REDCap), wearable sensors (Fitbit), and electronic health records.

Main Results:

Primary outcome: NIH Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Interference scale.
Secondary outcomes include PROMIS Anxiety, PROMIS Sleep Disturbance, and opioid prescription data.
Subgroup analyses will examine patient-level predictors of VR effectiveness.

Conclusions:

The NIH BACPAC VR trial protocol is established to rigorously evaluate VR for cLBP.
Findings will contribute to understanding VR's role in non-pharmacological chronic pain management.
Results will be disseminated via peer-reviewed publication.