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Updated: Nov 2, 2025

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Published on: September 24, 2020
Diffuse alveolar haemorrhage secondary to haemophilus influenzae in a vaping patient
Aahd Kubbara1, Feras Hawari2, John Johnkoski3
1Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA kubbara.aahd@mayo.edu.
Abstract:
Diffuse alveolar haemorrhage (DAH) is known to occur from several infectious and non-infectious aetiologies. Among the infectious aetiologies, Haemophilus influenzae, an organism known to cause community-acquired pneumonia, has not been reported in association with DAH prior to this case. On the other hand, vaping, an evolving epidemic concern, has been linked to various types of lung injury, including DAH. However, DAH related to vaping is only limited to several case reports. Our case describes H. influenzae pneumonia with DAH in a patient known to have vaped until the night prior to elective lobectomy for lung cancer and developed DAH within 24 hours of hospitalisation. He subsequently recovered with treatment. DAH requires immediate recognition, and healthcare providers need to be aware that neither haemoptysis nor decrease in haemoglobin level is necessarily associated. Prior to diagnosis, empirical treatment with intravenous steroids and antibiotics can be life-saving.
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