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Related Experiment Video

Updated: Nov 2, 2025

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver
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[Preoperative liver venous deprivation].

David Martin1, Ismail Labgaa1, Emilie Uldry1

  • 1Service de chirurgie viscérale, CHUV, 1011 Lausanne.

Revue Medicale Suisse
|June 16, 2021
PubMed
Summary

Liver venous deprivation (LVD) offers a promising solution for patients needing major liver resections. This technique enhances liver hypertrophy more effectively than traditional methods, improving surgical candidacy and outcomes.

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Area of Science:

  • Hepatobiliary Surgery
  • Interventional Radiology
  • Surgical Oncology

Background:

  • Major liver resections for hepato-biliary cancers can lead to post-hepatectomy liver failure.
  • Portal vein embolization (PVE) is used to increase remnant liver volume before surgery.
  • PVE has limitations, with up to 20% of patients experiencing insufficient hypertrophy or tumor progression.

Purpose of the Study:

  • To evaluate the efficacy and safety of Liver Venous Deprivation (LVD) as a preoperative liver-boosting technique.

Main Methods:

  • Liver Venous Deprivation (LVD) involves combined ipsilateral portal and hepatic vein embolization.
  • This technique aims to induce faster and more significant remnant liver hypertrophy.

Main Results:

  • LVD demonstrated faster and more substantial liver hypertrophy compared to conventional methods.
  • The procedure was associated with a low rate of complications.
  • No mortality was reported in association with the LVD procedure.

Conclusions:

  • Liver Venous Deprivation (LVD) is an effective and safe technique for preoperative liver hypertrophy.
  • LVD may improve the eligibility of patients for major liver resections by ensuring adequate remnant liver volume.
  • This approach offers a potential solution to the limitations of standard portal vein embolization.