Related Experiment Video
Updated: Nov 2, 2025
04:23
Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
2.5K
Primary hepatic adenosquamous carcinoma: A rare case report
Dong Wei1, Liu Lu2, Chen Ying1
1Department of General Surgery, Zhejiang Putuo Hospital, Zhoushan, China.
Indian Journal of Pathology & Microbiology
|June 17, 2021
Summary
Primary hepatic adenosquamous carcinoma (ASC) is a rare liver cancer easily mistaken for other types. This case report details a successful laparoscopic hepatectomy for ASC, offering insights into this challenging diagnosis and treatment.
Area of Science:
- Hepatobiliary surgery
- Gastroenterology
- Oncology
Background:
- Primary hepatic adenosquamous carcinoma (ASC) is an exceptionally rare liver malignancy.
- ASC presents a diagnostic challenge, often misdiagnosed as hepatocellular carcinoma preoperatively.
- It exhibits combined adenocarcinoma and squamous cell carcinoma features, with a 2-3% incidence in intrahepatic cholangiocarcinoma.
Observation:
- A male patient presented with upper abdominal pain for two months.
- Diagnosis of primary hepatic ASC was confirmed via histology and immunohistochemistry post-laparoscopic hepatectomy.
- The patient experienced no recurrence and maintained good health for two years post-surgery.
Findings:
- Laparoscopic hepatectomy can be a viable treatment for primary hepatic ASC.
- Histopathology and immunohistochemistry are crucial for accurate ASC diagnosis.
- Early recognition and surgical intervention are vital due to the poor prognosis associated with ASC.
Implications:
- This case highlights the importance of considering ASC in liver cancer differential diagnoses.
- Improved diagnostic strategies and treatment protocols for hepatic ASC are needed.
- Further research into the epidemiology, etiology, and long-term outcomes of hepatic ASC is warranted.
