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Related Concept Videos

Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Visual Evoked Potentials in Operated Primary Congenital Glaucoma: A Cross-Sectional Comparative Study.

Mai A Mohammed1, Mohamed Saad Morsy1, Nashwa Shehata Zeater2

  • 1Ophthalmology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Clinical Ophthalmology (Auckland, N.Z.)
|June 17, 2021
PubMed
Summary

Operated primary congenital glaucoma (PCG) eyes showed normal visual evoked potential (VEP) parameters compared to healthy children. This suggests successful surgical control in PCG leads to comparable visual pathway function.

Keywords:
electrophysiologyoptic nerveprimary congenital glaucomavisual evoked potentials

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Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Neuro-ophthalmology

Background:

  • Primary congenital glaucoma (PCG) is a severe pediatric eye condition requiring surgical intervention.
  • Assessing visual pathway function post-surgery is crucial for understanding long-term outcomes.
  • Visual evoked potential (VEP) testing can evaluate the integrity of the visual pathway.

Purpose of the Study:

  • To evaluate visual evoked potential (VEP) parameters in surgically managed primary congenital glaucoma (PCG) eyes.
  • To compare VEP parameters between operated PCG eyes and age-matched healthy children's eyes.

Main Methods:

  • A cross-sectional comparative study included 26 children with operated PCG and 22 age-similar controls.
  • Standard ophthalmic examination and electrophysiological testing (single flash VEP) were performed.
  • VEP parameters analyzed included P2 implicit time and N1-P1, N2-P2 amplitudes.

Main Results:

  • No statistically significant differences were found in VEP parameters (P2 implicit time, N1-P1, N2-P2 amplitudes) between operated PCG eyes and control eyes.
  • The mean age of study participants and controls was comparable.
  • No significant correlation was observed between clinical characteristics and VEP parameters in PCG eyes.

Conclusions:

  • Surgically controlled primary congenital glaucoma (PCG) eyes demonstrate visual evoked potential (VEP) parameters similar to those of healthy children.
  • These findings suggest that successful surgical management of PCG results in normal visual pathway function as assessed by VEP.